DIHYDRORHODAMINE 123, FOR FLUOR-ESCENCE
Dihydrorhodamine 123
CAS: 109244-58-8
Molecular Formula: C21H18N2O3
DIHYDRORHODAMINE 123, FOR FLUOR-ESCENCE - Names and Identifiers
DIHYDRORHODAMINE 123, FOR FLUOR-ESCENCE - Physico-chemical Properties
| Molecular Formula | C21H18N2O3 |
| Molar Mass | 346.38 |
| Density | 1.313±0.06 g/cm3(Predicted) |
| Melting Point | 163–165℃ |
| Boling Point | 526.9±50.0 °C(Predicted) |
| Solubility | DMSO: >5mg/mL |
| Appearance | Pink powder |
| Color | Light red or pinkish-white |
| Maximum wavelength(λmax) | ['289 nm'] |
| BRN | 5989965 |
| pKa | 4.70 ± 0.40, most basic, temperature:25 °C |
| Storage Condition | -20°C |
| MDL | MFCD00285712 |
| Use | Peroxidase substrate |
| In vitro study | In the presence of 10 μM Dihydrorhodamine 123 (DHR 123) the stimulation of the neutrophil NADPH oxidase by the addition of 50 nM phorbol 12-myristate 13-acetat (PMA) resultes in an increase in the rate of rhodamine generation. The fluorescent intensity of the cells, in the presence of 10 μM Dihydrorhodamine 123, increases with time following the addition of 50 nM PMA. In the presence of 10 μM Dihydrorhodamine 123, induced HL60 cells show a sustained increase in fluorescence following the addition of 50 nM PMA. |
DIHYDRORHODAMINE 123, FOR FLUOR-ESCENCE - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-23 |
DIHYDRORHODAMINE 123, FOR FLUOR-ESCENCE - Reference
| Reference Show more | 1. Xue Liu, Jiaxin Cai, Haiming Chen, Qiuping Zhong, Yaqi Hou, Weijun Chen, Wenxue Chen,Antibacterial activity and mechanism of linalool against Pseudomonas aeruginosa,Microbial Pathogenesis,Volume 141,2020,103980,ISSN 0882-4010,https://doi.org/10.1016 2. [IF=8.273] Sun Yujie et al."Flexible electrostatic hydrogels from marine organism for nitric oxide-enhanced photodynamic therapy against multidrug-resistant bacterial infection."Science China-Materials. 2022 Apr;:1-11 |
DIHYDRORHODAMINE 123, FOR FLUOR-ESCENCE - Reference Information
| biological application | Generating,detecting & measuring reactive oxygen species; generating,detecting & measuring reactive nitrogen species; detecting phosphates,peroxynitrile; measuring respiratory burst; chronic granulomatous disease DHR say; screening |
| biological activity | Dihydrorhodamine 123 (DHR 123) is a fluorescent probe (λex = 488 nm,λem = 525 nm). |
| use | peroxidase substrate |
Last Update：2024-04-09 21:04:16
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